Page 7 - CH6 (1)
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Properties of the Genetic Material

                   ● It should be able to replicate (duplicate to produce its identical copy).
                   ● It should be chemically and structurally stable.

                   ● It should have scope for changes that are essential for evolution.
                   ● It should follow the Mendelian principles of inheritance.

                   ● Difference between DNA and RNA:


                               DNA                                         RNA


                        ○ Has deoxyribose                           ○ Has ribose sugar

                                  sugar

                         ○ 5­methyl uracil                    ○ Uracil is present in place of

                         (thymine) is present.                              thymine.


                      ○ Mostly DNA acts as                  ○ RNA acts as a messenger and
                         the genetic material.                   adaptor. It acts as a genetic

                                                                   material in some viruses.


                         ○ DNA is stable.                 ○ Presence of 2′ OH group at every
                                                              nucleotide makes RNA labile and
                                                                     easily biodegradable.


                         ○ Chemically less                     ○ Mutation in RNA is faster.

                           reactive, mutates
                                  slowly


                     ○ DNA requires RNA for                ○ RNA directly codes for proteins.
                           protein synthesis.

                                          P


                        DNA ​​RNA ​​rotein
                                       →
                              →
                       Why DNA is more stable than RNA?
                   ● In RNA, a 2′ OH group is present at every nucleotide. This makes RNA
                       unstable and degradable.

                   ● Presence of thymine in place of uracil confers additional stability to
                       DNA.
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