Page 13 - Lesson Notes- Principle of inheritance & Variation
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non-sister chromatics of homologous                2. It involves individual chromosomes.

                chromosomes.



                                                                   3. The number of linkage group can
                3. The frequency of crossing over can never
                                                                   never be  more than haploid
                exceed 50%.
                                                                   Chromosome number.


                4. It increases variability by  forming new
                                                                   4. It reduces variability.
                gene combinations.



       Sex Determination


               Henking in 1891  observed a trace of specific nuclear structure  in few  insects. He  also

               observed that this specific nuclear structure  is located on 50%  of sperms only. He called

               this x body. He  was  not able to  explain its  significance.
               Latter it was  observed that the ovum that receive the sperms with x body become

               female and those not becomes males, so  this x body was  called as  sex chromosome

               and other chromosomes are called autosomes.
               In humans and other organisms XY types of sex  determination is seen but in some

               insects like  Drosophila XO type of sex  determination is present.

               In both types of sex  determination, male produce two  different types of gametes either
               with or without X chromosome or some with X chromosome and some with Y

               chromosomes. Such types of sex  determination are called male heterogamety.
               In birds ZW type of sex  determination is present., two  different types of gametes are

               produced by  females in terms of sex  chromosomes; this type of sex  determination is

               called female heterogamety.
               Sex determination in  human beings XY type. Out of 23 pairs of chromosomes, 22 pairs

               are exactly same in male and female called autosomes. A pair of X chromosome is
               present in female and XY in male. During spermatogenesis, male produce two  type of

               gametes (sperms), 50%  carries Y chromosome and remaining 50%  contain X

               chromosome. Female, produce only one kind of gamete (ovum) having X chromosomes
               only.








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